Spotlight · Health
HackedSelf
Evidence-first biohacking: protocol doses, effect sizes, cost-per-session math, and the n=1 caveats stated plainly
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HackedSelf is a biohacking site for people who want the evidence, not the hype. Every protocol gets the same treatment: what the studies actually measured, how big the effect is, and what the n=1 caveats are before anyone spends money or buys equipment. Recent pieces show the method. A sauna-vs-cardio comparison asks whether a home sauna protocol can replace Zone 2 work, and answers with a minimum dose: four sessions above 175°F, not vibes. A strength-training piece tests the 'muscle age' idea through grip strength, gait, and lower-body power instead of mirror gains. A semaglutide review reads the longevity evidence honestly: real, but narrow, with the data caveat being HIV-patient cohorts rather than healthy-world trials. Cost math gets its own series, because protocols are easier to start than to afford. The home sauna running-cost breakdown computes cost per session against the gym sauna lounge and finds the break-even point. The XPRIZE Healthspan results get audited against the actual rules: AgelessRx involvement, and 90-day results scored against 12-month claims. Zone 2 training for lifters is dosed like a protocol, with session structure and targets, not a motivational essay. No invented effect sizes, no supplement-store metaphysics: effect sizes, doses, costs, and the caveats the influencer posts leave out.
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